I Small Molecule Metabolism I.A Amino acid biosynthesis I.A.1 leucine I.A.2 isoleucine/valine I.A.3 alanine I.A.4 histidine I.A.5 chorismate I.A.6 tryptophan I.A.7 tyrosine I.A.8 phenylalanine I.A.9 cysteine I.A.10 serine I.A.11 glycine I.A.12 methionine I.A.12 threonine I.A.13 lysine I.A.14 asparagine I.A.15 aspartate I.A.16 proline I.A.17 arginine I.A.18 glutamine I.A.19 glutamate I.B Biosynthesis of cofactors, carriers I.B.1 fatty acid and phosphatidic acid biosynthesis I.B.2 enterochelin I.B.3 cobalamin I.B.4 heme, porphyrin I.B.5 menaquinone, ubiquinone I.B.6 thioredoxin, glutaredoxin, glutathione I.B.7 riboflavin I.B.8 thiamin I.B.9 pyridine nucleotide I.B.10 pyridoxine I.B.11 pantothenate I.B.12 molybdopterin I.B.13 lipoate I.B.14 folic acid I.B.15 biotin I.B.16 acyl carrier protein (ACP) I.B.17 biotin carboxyl carrier protein (BCCP) I.C Fatty acid biosynthesis I.D Nucleotide biosynthesis I.D.1 pyrimidine ribonucleotide biosynthesis I.D.2 purine ribonucleotide biosynthesis I.E Global functions I.E.1 global regulatory functions I.E.2 ATP-proton motive force interconversion I.F Central intermediary metabolism I.F.1 salvage of nucleosides and nucleotides I.F.2 2-prime-deoxyribonucleotide metabolism I.F.3 sulfur metabolism I.F.4 misc. glucose metabolism I.F.5 nitrogen metabolism I.F.6 nitrogen fixation I.F.7 oligosaccharides I.F.8 amino sugars I.F.9 nucleotide interconversions I.F.10 sugar-nucleotide biosynthesis, conversions I.F.11 misc. glycerol metabolism I.F.12 nucleotide hydrolysis I.F.13 gluconeogenesis I.F.14 amino acids I.F.15 polyamine biosynthesis I.F.16 Entner-Doudoroff I.F.17 glyoxylate bypass I.F.18 pool of unassigned individual reversibles reactions I.F.19 non oxidative branch, pentose pathway I.F.20 phosphorus metabolism I.G Energy transfer I.G.1 electron transport I.H Energy metabolism, carbon I.H.1 fermentation I.H.2 anaerobic respiration I.H.3 aerobic respiration I.H.4 oxidative branch, pentose pathway I.H.6 TCA cycle I.H.7 pyruvate dehydrogenase I.H.8 glycolysis I.I Degradation I.I.1 fatty acid I.I.2 amines I.I.3 amino acids I.I.4 carbon compounds II MACROMOLECULE METABOLISM II.A Macromolecule degradation II.A.1 degradation of DNA II.A.2 degradation of RNA II.A.3 degradation of polysaccharides II.A.4 degradation of proteins, peptides, glycopeptides II.B Macromolecule synthesis, modification II.B.1 phospholipides II.B.2 lipopolysaccharides II.B.3 glycoproteins II.B.4 lipoproteins II.B.5 polysaccharides - (cytoplasmic) II.B.6 RNA synthesis, modification , DNA transcription II.B.7 proteins and peptides - translation and modification II.B.8 DNA - replication, repair, restr./modif. II.C Basic proteins II.C.1 basic proteins - synthesis, modification II.D aa-tRNAs II.D.1 amino acyl tRNA synthesis; tRNA modification II.D.2 tRNA III STRUCTURAL ELEMENTS III.A Cell Exterior III.A.1 surface polysaccharides/antigens III.A.2 surface structures III.B Cell envelope III.B.1 membrane, inner III.B.2 membrane, outer III.B.3 murein sacculus, peptidoglycan III.C Ribosome constituents III.C.1 ribosomes - maturation and modification III.C.2 ribosomal proteins - synthesis, modification III.C.3 ribosomal and stable RNAs IV CELL PROCESSES IV.A Cell division IV.B Chaperoning IV.C Mobility chemotaxis IV.D Transport of small molecules IV.D.1 anions IV.D.2 amino acids, amines IV.D.3 carbohydrates, organic acids, alcohols IV.D.4 cations IV.D.5 incorporation metal ions IV.D.6 nucleosides, purines pyrimidines IV.D.7 other transport IV.E Transport of large molecules IV.E.1 uptake of DNA IV.E.2 protein, peptide secretion IV.F Adaptation IV.F.1 adaptations, atypical conditions IV.F.2 osmotic adaptation IV.G Protection responses IV.G.1 radiation sensitivity IV.G.2 drug/analog sensitivity IV.G.3 cell killing IV.G.4 detoxification IV.H Nodulation V ELEMENTS OF EXTERNAL ORIGIN V.A Transposon-related functions V.B Plasmid-related functions Non-bacterial functions V.C Colicin-related functions Non-bacterial functions V.D Phage-related functions and prophages VI MISCELLANEOUS VI.A Not classified regulator VI.B Hypothetical/Partial homology VI.C Hypothetical/Global homology VI.E Virulence VI.D Unknown